Medal Lectures online

AstraZeneca Award Lecture

Synchrotron radiation circular dichroism (SRCD) spectroscopy: an enhanced method for examining protein conformations and protein interactions

B.A. Wallace and Robert W. Janes..........38 861-873

Delivered at University of Sheffield, on 12 January 2010

The impact of phage lambda: from restriction to recombineering

Noreen E. Murray..........34 203-207

Delivered at AstraZeneca, Loughborough, on 21 November 2005

New tricks with isotopically enriched oligosaccharides

S.W. Homans...........26 551-560

Delivered at the University of Southampton, on 31 March 1998

Biochemical Society Award Lecture

Tuberculosis: a balanced diet of lipids and carbohydrates

Veemal Bhowruth, Luke J. Alderwick, Alistair K. Brown, Apoorva Bhatt and Gurdyal S. Besra..........36 555–565

Delivered at the University of Birmingham, on 13 March 2008

The mystery of intracellular developmental programmes and timers

M. Raff.........34 663-670

Delivered at the SECC, Glasgow, on 27 July 2006

How to (or not to) communicate science

S.P.R. Rose..........31 307-312

Delivered at the Royal Institution, London, on 24 October 2002, and at the Whitworth Art Gallery, Manchester, on 21 November 2002

Genes in food - why the furore?

B. Dixon..........31 299-306

Delivered at the Royal Institution, London, on 24 October 2002, and at the Whitworth Art Gallery, Manchester, on 21 November 2002

Biochemical Society Special Lecture

Nitrate- and nitrite-responsive sensors NarX and NarQ of proteobacteria

V. Stewart..........31 1-10

Delivered at the University of Newcastle, on 30 August 2002

CIBA Medal Lecture

Regulatory roles of the nuclear membrane

R.A. Laskey...........26 561-567

Delivered at the University of Dundee, 30 July 1997

Colworth Medal Lecture

Coupling of the NMDA receptor to neuroprotective and neurodestructive events

Giles E. Hardingham...........37 1147-1160

Delivered at University of St Andrews on 23 July 2009

Control of genome stability by Slx protein complexes

John Rouse..........37 495–510

Delivered at Robinson College, Cambridge, on 16 December 2008

The twin-arginine transport system: moving folded proteins across membranes

F. Sargent.........35 835-847

Delivered at the SECC, Glasgow, on 12 July 2007

Cellular functions of the BRCA tumour-suppressor proteins

S.J. Boulton.........34 633-645

Delivered at the SECC, Glasgow, on 26 July 2006

The structure of the bacterial protein translocation complex SecYEG

I. Collinson..........33 1225-1230

Delivered at the SECC, Glasgow, on 21 July 2005

Chemical insights from structural studies of enzymes

J.H. Naismith..........32 647-654

Delivered at the SECC, Glasgow, on 21 July 2004

Linking endocytic cargo to clathrin: structural and functional insights into coated vesicle formation

D.J. Owen..........32 1-14

Delivered at the University of Essex, on 2 July 2003

Pathways for remodelling chromatin

T. Owen-Hughes..........31 893-905

Delivered at Cardiff University, on 17 July 2002

Complexities in ETS-domain transcription factor function and regulation: lessons from the TCF (ternary complex factor) subfamily

A.D. Sharrocks..........30 1-9

Delivered at the University of York, on 18 December 2001

Discovery of PDK1, one of the missing links in insulin signal transduction

D.R. Alessi..........29 1-14

Delivered at the University of Bath, on 4 September 2000

Enzymes in the Quantum World

N.S. Scrutton............27 767-779

Delivered at University College, Cork, on 7 September 1999

Structural studies of reversible protein phosphorylation and protein phosphatases

D. Barford............27 751-766

Delivered at the University of Southampton, on 31 March 1998

Detection, repair and signalling of DNA double-strand breaks

S.P. Jackson............27 1-13

Delivered at the University of Reading, on 15 December 1997

Early Career Research Award

Endogenous ion channel complexes: the NMDA receptor

René A.W. Frank.........39 707‑718

Delivered at Robinson College, Cambridge, on 5 January 2011

The ESCRT machinery: a cellular apparatus for sorting and scission

Jeremy Carlton.........38 1397-1412

Delivered at Charles Darwin House, London, on 13 May 2010

Structure, evolution and dynamics of transcriptional regulatory networks

M. Madan Babu..........38 1155–1178

Delivered at University of York, on 23 March 2010

The emerging complexity of protein ubiquitination

David Komander..........37 937–953

Delivered at Appleton Tower, University of Edinburgh on 2 April 2009

Membrane proteins in nanotechnology

Paul Curnow..........37 643–652

Delivered at Robinson College, Cambridge, on 8 January 2009

GlaxoSmithKline Award Lecture

The O-GlcNAc modification: three-dimensional structure, enzymology and the development of selective inhibitors to probe disease

Gideon J. Davies and Carlos Martinez-Fleites..........38 1179-1188

Delivered at Royal Holloway University of London, on 30 March 2010

The DNA-damage response: new molecular insights and new approaches to cancer therapy

Stephen P. Jackson..........37 483-494

Delivered at Robinson College, Cambridge, on 15 December 2008

Caspase activation cascades in apoptosis

Susan E. Logue and Seamus J. Martin.........36 1–9

Delivered at the SECC, Glasgow, on 25 July 2006

Molecular mousetraps and the serpinopathies

D.A. Lomas, D. Belorgey, M. Mallya, E. Miranda, K.J. Kinghorn, L.K. Sharp, R.L. Phillips, R. Page, A.S. Robertson and D.C. Crowther..........33 321-330

Delivered at the Royal Institute of British Architects, London, on 17 November 2004

Heatley Medal Lecture

What we have learned from ribosome structures

V. Ramakrishnan.........36 567–574

Delivered at the University of Manchester, on 26 March 2008

Jubilee Lecture

miRNPs: versatile regulators of gene expression in vertebrate cells

Joan A. Steitz and Shobha Vasudevan..........37 931–935

Delivered at Appleton Tower, University of Edinburgh on 2 April 2009

Alternative mechanisms of initiating translocation of mammalian mRNAs

R. Jackson..........33 1231-1241

Delivered at the SECC, Glasgow, on 21 July 2005

Vascular zip codes in angiogenesis and metastasis

E. Ruoslahti..........32 397-402

Delivered at the Chancellors Conference Centre, University of Manchester, on 1 December 2003

Role of Src in signal transduction pathways

S.A. Courtneidge..........30 11-18

Delivered at the University of Bristol, on 10 April 2001

The chemical and biological versatility of riboflavin

V. Massey..........28 283-296

Delivered at King's College, London, on 19 November 1999, and at the University of Leeds, on 22 November 1999

Keilin Memorial Lecture

A pore way to die: the role of mitochondria in reperfusion injury and cardioprotection

Andrew P. Halestrap...........38 841-860

Delivered at Holiday Inn, Bloomsbury, London, on 26 March 2010

The efficiency and plasticity of mitochondrial energy transduction

M.D. Brand..........33 897-904

Delivered at the SECC, Glasgow, on 20 July 2005

The molecular machinery of Keilin's respiratory chain

P.R. Rich..........31 1095-1105

Delivered at the University of Essex, on 3 July 2003

Keilin's cytochromes: how bacteria use them, vary them and make them

S.J. Ferguson..........29 629-640

Delivered at Trinity College, Dublin, on 12 July 2001

X-ray structure and reaction mechanism of bovine heart cytochrome c oxidase

S. Yoshikawa............27 351-362

Delivered at the University of Glasgow, on 8 April 1999

Morton Lecture

Phosphoinositides and the regulation of tubular-based endosomal sorting

Peter Cullen..........37 839–850

Delivered at the Royal Agricultural College, Cirencester, on 10 September 2010

Form and flexibility in phosphoinositide 3-kinases

Roger Williams, Alex Berndt, Simon Miller, Wai-Ching Hon and Xuxiao Zhang..........37 615–626

Delivered at Medical Sciences Teaching Centre, University of Oxford, on 15 September 2008

Signalling through Class I PI3Ks in mammalian cells

P.T. Hawkins, K.E. Anderson, K. Davidson and L.R. Stephens.........34 647-662

Delivered at the SECC, Glasgow, on 27 July 2006

The ubiquitous phosphoinositides

P.J. Parker..........32 893-898

Delivered at the SECC, Glasgow, on 19 July 2004

New insights into the roles of phosphoinositides and inositol polyphosphates in yeast

R.H. Michell, N.M. Perera and S.K. Dove..........31 11-15

Delivered at the University of Liverpool, on 4 September 2002

Novartis Medal Lecture

AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer

D. Grahame Hardie..........39 1‑13

Delivered at the Royal Agricultural College, Cirencester, on 11 September 2010

The regulation of protein phosphorylation

Louise N. Johnson..........37 627–641

Delivered at Wellcome Trust Conference Centre, Cambridge, on 26 January 2009

The search for a human Holliday junction resolvase

Stephen C. West..........37 519-526

Delivered at Robinson College, Cambridge, on 17 December 2008

The methyl-CpG-binding protein MeCP2 and neurological disease

Adrian Bird.........36 575–583

Delivered at the University of Manchester, on 28 March 2008

Photosystem II: an enzyme of global significance

J. Barber.........34 619-631

Delivered at the SECC, Glasgow, on 25 July 2006

Rho GTPases and the control of cell behaviour

A. Hall..........33 891-895

Delivered at the SECC, Glasgow, on 19 July 2005

Lsm proteins and RNA processing

J.D. Beggs..........33 433-438

Delivered at the University of Edinburgh, on 4 December 2004

Modular proteins at the cell surface

I.D. Campbell..........31 1107-1114

Delivered at the University of Essex, on 3 July 2003

Antibodies: a paradigm for the evolution of molecular recognition

M.S. Neuberger..........30 341-350

Delivered at Heriott-Watt University, Edinburgh, on 9 April 2002

Hopping, jumping and looping by restriction enzymes

S.E. Halford..........29 363-373

Delivered at the University of Bristol, on 12 April 2001

Structure and assembly of the spliceosomal snRNPs

K. Nagai, Y. Muto, D.A. Pomeranz Krummel, C. Kambach, T. Ignjatovic, S. Walke and A. Kuglstatter..........29 15-29

Delivered at the University of Sussex, on 19 December 2000

Small GTPases and cell cycle regulation

C.J. Marshall............27 363-370

Delivered at the University of Glasgow, on 7 April 1999

Rank Prize Funds Lecture

Barrett's metaplasia: molecular mechanisms and nutritional influences

Jonathan M.W. Slack, Benjamin J. Colleypriest, Jonathan M. Quinlan, Wei-Yuan Yu, J. Mark Farrant and David Tosh..........38 313-319

Delivered at University of Bath, on 17 September 2009

Royal Irish Academy Medal Lecture

Thromboxane A2 signalling in humans: a 'tail' of two receptors

B.T. Kinsella..........29 641-653

Delivered at Trinity College, Dublin, on 10 July 2001

Using NMR as a probe of protein structure and function

J.P.G. Malthouse............27 701-713

Delivered at Dublin City University, Dublin, on 10 September 1998

Sir Frederick Gowland Hopkins Memorial Lecture

Functions of p53 in metabolism and invasion

Karen H. Vousden..........37 511-517

Delivered at Robinson College, Cambridge, on 16 December 2008

Society and the human genome

J. Sulston and the International Human Genome Sequencing Consortium..........29 27-31

Delivered at the University of Sussex, on 20 December 2000

Pleasant surprises en route from the biochemistry of collagen to attempts at gene therapy

D.J. Prockop............27 15-31

Delivered at the University of Sheffield, 30 July 1998

Thudichum Medal Lecture

L-Glutamate as a central neurotransmitter: looking back

J.C. Watkins..........28 297-309

Delivered at the University of Leeds, on 11 April 2000

Wellcome Trust Award Lecture

Chromatin-modifying enzymes in transcription and cancer

T. Kouzarides..........31 741-743

Delivered at Imperial College, London, on 16 December 2002

Integrin structure

M.J. Humphries..........28 311-339

Delivered at the University of Leeds, on 12 April 2000