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Most Read papers

Which papers published in the last 3 years are being downloaded the most?
The number of downloads in the 12 months to the end of November 2011 are shown below

1666 The involvement of microRNAs in Type 2 diabetes
David Ferland-McCollough, Susan E Ozanne, Kenneth Siddle, Anne E Willis and Martin Bushell
(2010) 38, 1565-1570 doi:10.1042/BST0381565
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1608 Inflammasome activation: from inflammatory disease to infection
Aisling Dunne
(2011) 39, 669-673 doi:10.1042/BST0390669
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1565 PI3K inhibitors for cancer treatment: where do we stand?
Sauveur-Michel Maira, Frédéric Stauffer, Christian Schnell and Carlos García-Echeverría
(2009) 37, 265-272 doi:10.1042/BST0370265
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1535 The emerging complexity of protein ubiquitination
David Komander
(2009) 37, 937-953 doi:10.1042/BST0370937
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1388 The delivery of endocytosed cargo to lysosomes
J Paul Luzio, Michael D J Parkinson, Sally R Gray and Nicholas A Bright
(2009) 37, 1019-1021 doi:10.1042/BST0371019
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1232 AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer
D Grahame Hardie
(2011) 39, 1-13 doi:10.1042/BST0390001
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1200 Endosome-lysosome fusion
J Paul Luzio, Sally R Gray and Nicholas A Bright
(2010) 38, 1413-1416 doi:10.1042/BST0381413
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1188 The ground state of pluripotency
Jason Wray, Tuzer Kalkan and Austin G Smith
(2010) 38, 1027-1032 doi:10.1042/BST0381027
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1147 53BP1: function and mechanisms of focal recruitment
Jennifer E FitzGerald, Muriel Grenon and Noel F Lowndes
(2009) 37, 897-904 doi:10.1042/BST0370897
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1130 Exploring the LPS/TLR4 signal pathway with small molecules
Francesco Peri, Matteo Piazza, Valentina Calabrese, Gaetana Damore and Roberto Cighetti
(2010) 38, 1390-1395 doi:10.1042/BST0381390
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1123 A complex interplay between Akt, TSC2 and the two mTOR complexes
Jingxiang Huang and Brendan D Manning
(2009) 37, 217-222 doi:10.1042/BST0370217
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1112 VEGFRs and Notch: a dynamic collaboration in vascular patterning
Lars Jakobsson, Katie Bentley and Holger Gerhardt
(2009) 37, 1233-1236 doi:10.1042/BST0371233
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1102 Cutting the nonsense: the degradation of PTC-containing mRNAs
Pamela Nicholson and Oliver Mühlemann
(2010) 38, 1615-1620 doi:10.1042/BST0381615
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1089 On track with P-bodies
Meeta Kulkarni, Sevim Ozgur and Georg Stoecklin
(2010) 38, 242-251 doi:10.1042/BST0380242
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1077 Protein-protein interactions
Mike P Williamson and Michael J Sutcliffe
(2010) 38, 875-878 doi:10.1042/BST0380875
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1063 Nutrient-dependent regulation of autophagy through the target of rapamycin pathway
Yu-Yun Chang, Gábor Juhász, Pankuri Goraksha-Hicks, Andrew M Arsham, Daniel R Mallin, Laura K Muller and Thomas P Neufeld
(2009) 37, 232-236 doi:10.1042/BST0370232
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1057 Interaction proteomics: characterization of protein complexes using tandem affinity purification-mass spectrometry
Pamela Völkel, Perrine Le Faou and Pierre-Olivier Angrand
(2010) 38, 883-887 doi:10.1042/BST0380883
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982 Alix and ALG-2 make a link between endosomes and neuronal death
Anne-Laure Mahul-Mellier, Flavie Strappazzon, Christine Chatellard-Causse, Béatrice Blot, David Béal, Sakina Torch, Fiona Hemming, Anne Petiot, Jean-Marc Verna, Sandrine Fraboulet and Rémy Sadoul
(2009) 37, 200-203 doi:10.1042/BST0370200
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951 Post-transcriptional and post-translational regulation of Bcl2
Shaun Willimott and Simon D Wagner
(2010) 38, 1571-1575 doi:10.1042/BST0381571
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941 Inflammation: a role for NR4A orphan nuclear receptors?
Jason P McMorrow and Evelyn P Murphy
(2011) 39, 688-693 doi:10.1042/BST0390688
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930 Cytoplasmic deadenylation: regulation of mRNA fate
Katrin Wiederhold and Lori A Passmore
(2010) 38, 1531-1536 doi:10.1042/BST0381531
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910 Regulation and biological function of the liver-specific miR-122
Andrew P Lewis and Catherine L Jopling
(2010) 38, 1553-1557 doi:10.1042/BST0381553
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908 Pathogenic mechanisms of myotonic dystrophy
Johanna E Lee and Thomas A Cooper
(2009) 37, 1281-1286 doi:10.1042/BST0371281
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895 The anaphase-promoting complex/cyclosome (APC/C): cell-cycle-dependent and -independent functions
Eusebio Manchado, Manuel Eguren and Marcos Malumbres
(2010) 38, 65-71 doi:10.1042/BST0380065
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895 mTOR Signalling in Health and Disease
Christopher G Proud
(2011) 39, 431-436 doi:10.1042/BST0390431
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875 The role of ESCRT proteins in fusion events involving lysosomes, endosomes and autophagosomes
Daniel Metcalf and Adrian M Isaacs
(2010) 38, 1469-1473 doi:10.1042/BST0381469
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872 The ‘anaphase problem‘: how to disable the mitotic checkpoint when sisters split
María Dolores Vázquez-Novelle, Lesia Mirchenko, Frank Uhlmann and Mark Petronczki
(2010) 38, 1660-1666 doi:10.1042/BST0381660
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871 Regulation of the SREBP transcription factors by mTORC1
Caroline A Lewis, Beatrice Griffiths, Claudio R Santos, Mario Pende and Almut Schulze
(2011) 39, 495-499 doi:10.1042/BST0390495
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864 miR-21 as a key regulator of oncogenic processes
S Duygu Selcuklu, Mark T A Donoghue and Charles Spillane
(2009) 37, 918-925 doi:10.1042/BST0370918
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836 The evolution of protein domain families
Marija Buljan and Alex Bateman
(2009) 37, 751-755 doi:10.1042/BST0370751
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820 Exosome target cell selection and the importance of exosomal tetraspanins: a hypothesis
Sanyukta Rana and Margot Zöller
(2011) 39, 559-562 doi:10.1042/BST0390559
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801 A longer and healthier life with TOR down-regulation: genetics and drugs
Ivana Bjedov and Linda Partridge
(2011) 39, 460-465 doi:10.1042/BST0390460
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784 The dynamic Rab11-FIPs
Conor P Horgan and Mary W McCaffrey
(2009) 37, 1032-1036 doi:10.1042/BST0371032
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749 The regulation of protein phosphorylation
Louise N Johnson
(2009) 37, 627-641 doi:10.1042/BST0370627
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716 Getting through anaphase: splitting the sisters and beyond
Raquel A Oliveira and Kim Nasmyth
(2010) 38, 1639-1644 doi:10.1042/BST0381639
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690 Gene expression networks: competing mRNA decay pathways in mammalian cells
Lynne E Maquat and Chenguang Gong
(2009) 37, 1287-1292 doi:10.1042/BST0371287
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687 Genomic DNA amplification by the multiple displacement amplification (MDA) method
Roger S Lasken
(2009) 37, 450-453 doi:10.1042/BST0370450
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676 A new map to understand deubiquitination
Elijah J Katz, Marta Isasa and Bernat Crosas
(2010) 38, 21-28 doi:10.1042/BST0380021
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675 SUMO and ubiquitin paths converge
Amanda Denuc and Gemma Marfany
(2010) 38, 34-39 doi:10.1042/BST0380034
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674 Lysosomal membrane proteins: life between acid and neutral conditions
Paul Saftig, Bernd Schröder and Judith Blanz
(2010) 38, 1420-1423 doi:10.1042/BST0381420
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672 The therapeutic potential of deubiquitinating enzyme inhibitors
Frédéric Colland
(2010) 38, 137-143 doi:10.1042/BST0380137
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670 COLD-PCR: a new platform for highly improved mutation detection in cancer and genetic testing
Jin Li and G Mike Makrigiorgos
(2009) 37, 427-432 doi:10.1042/BST0370427
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663 Differing effects of rapamycin and mTOR kinase inhibitors on protein synthesis
Yilin Huo, Valentina Iadevaia and Christopher G Proud
(2011) 39, 446-450 doi:10.1042/BST0390446
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647 Pathways linking Abeta and tau pathologies
Frank M LaFerla
(2010) 38, 993-995 doi:10.1042/BST0380993
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640 A pore way to die: the role of mitochondria in reperfusion injury and cardioprotection
Andrew P Halestrap
(2010) 38, 841-860 doi:10.1042/BST0380841
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638 The impact of heterochromatin on DSB repair
Aaron A Goodarzi, Angela T Noon and Penny A Jeggo
(2009) 37, 569-576 doi:10.1042/BST0370569
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636 Pat1 proteins: a life in translation, translation repression and mRNA decay
Aline Marnef and Nancy Standart
(2010) 38, 1602-1607 doi:10.1042/BST0381602
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630 Structure and function of ESCRT-III
Suman Lata, Guy Schoehn, Julianna Solomons, Ricardo Pires, Heinrich G Göttlinger and Winfried Weissenhorn
(2009) 37, 156-160 doi:10.1042/BST0370156
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622 Mitochondrial quality control by the ubiquitin-proteasome system
Eric B Taylor and Jared Rutter
(2011) 39, 1509-1513 doi:10.1042/BST0391509
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620 Ubiquitin and SUMO signalling in DNA repair
Timothy M Thomson and Marta Guerra-Rebollo
(2010) 38, 116-131 doi:10.1042/BST0380116
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